E-cigarette use has risen at concerning levels among both smokers and non-smokers and now researchers from the Ohio State University have found that even short-term vaping could cause cellular inflammation in never-smoker adults.
Using a procedure called bronchoscopy to test for inflammation and smoking-related effects, researchers reported a measurable increase in inflammation after four weeks of e-cigarette use without nicotine or flavours.
The study suggested that even short-term usage could result in inflammatory changes at a cellular level.
"Through the randomised clinical trial of healthy never-smokers over a month, we found that an increase in urinary propylene glycol, a marker of inhalation-e-cig intake, was significantly correlated with increased inflammatory response in the lung," said the study's first author Min-Ae Song from Ohio State University.
For the study, researchers recruited 30 healthy, non-smoking volunteers to directly assess the impact of tobacco and e-cig use on the lungs through bronchoscopy, an outpatient test in which a doctor inserts a thin tube through the nose or mouth to view the airways.
A small sample of lung cells was collected from fluid in the lungs.
Participants were randomised to a four-week intervention with e-cigs containing only 50 per cent propylene glycol (PG) or 50 per cent vegetable glycerine (VG) without nicotine or flavours.
Results from these tests were then compared to a separate control group of never-smokers.
Researchers did not see levels of inflammation higher than the controls, but there was an increase in inflammation among the users who inhaled more of the e-cigarette.
With the recent reports of lung disease and deaths associated with vaping, the effects of vaping nicotine and marijuana oils makes this research more critical, said the researchers.
This article originally appeared at the IOL website